When a new version of Kronos Time Titan is release, there is usually new content that is incompatible with previous save data. In the past, this would require starting a brand new game and losing all collected items, unlockables, currency, and money.
Not anymore. Now when there is a new update, you can usually use the “SYCHRONIZE THE MATRIX” option from the main menu to sync the new content with the old save data.

This will rewind all of the timelines, which reverts all temporal story progress. However, you will keep your currency, energy, unlocked Titan Powers, clothes, acquired girls, and items.
If you update the game any something is not working properly, try Syncing the Matrix!